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Additives

BHA (E320): What It Is and Is It Safe?

Hazardous Antioxidant · Synthetic antioxidant

Synthetic antioxidant. Listed as "reasonably anticipated to be a human carcinogen" by the US National Toxicology Program. IARC classifies it as Group 2B (possibly carcinogenic). Banned in Japan.

Category
Antioxidant — Synthetic antioxidant
Typically used in
Crisps, crackers, instant noodles, chewing gum, cereals
Regulatory status
IARC Group 2B. Banned Japan. NTP carcinogen listing.
Also listed as
Butylated Hydroxyanisole
Concerns flagged
Possible allergenCarcinogenicity concernEndocrine disruptionGenotoxicity concernNeurotoxicity concernReproductive-health concernThyroid effects

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Sources

Where this comes from

  1. EFSA (2012) — Statement on the safety assessment of the exposure to butylated ydroxyanisole E 320 -BHA- by applying a new exposure assessment methodology http://dx.doi.org/10.2903/j.efsa.2012.2759
  2. IARC (1986) — IARC Monographs Vol. 40 – Butylated Hydroxyanisole BHA (Group 2B, possible human carcinogen) https://www.inchem.org/documents/iarc/vol40/butylatedhydroxyanisole.html
  3. Ao et al. (2023) — A review of the occurrence, metabolites and health risks of butylated hydroxyanisole (BHA) https://doi.org/10.1002/jsfa.12689
  4. Pandya et al. (2025) — Exploring the Mechanisms of BHA, BHT, and TBHQ in Hepatotoxicity, Nephrotoxicity, and Neurotoxicity from the Perspective of Network Toxicology https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11988534/
  5. Maisanaba et al. (2024) — Cytotoxic and genotoxic effects of tert-butylhydroquinone, butylated hydroxyanisole and propyl gallate as synthetic food antioxidants https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11521724/
Products

Products containing BHA

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